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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
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导致功能障碍的心血管疾病的全球负担和趋势,1990-2021年
1Department of Nephrology, Beilun People's Hospital, Ningbo, China.
Nephrology (Carlton, Vic.)
|November 8, 2025
概括
与功能障碍相关的全球心血管疾病负担在1990年至2021年之间总体下降. 然而,仍然存在显著的区域差异,一些地区显示出日益增长的趋势,特别是老龄化人口.
科学领域:
- 流行病学 流行病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 代表着全球健康的重大负担.
- 功能障碍越来越被认为是心血管疾病的主要危险因素.
- 了解可归因于功能障碍的心血管疾病负担的趋势对于公共卫生规划至关重要.
研究的目的:
- 从1990年到2021年分析与功能障碍相关的心血管疾病 (CVD) 的全球负担.
- 确定与功能障碍相关的心血管疾病负担的区域变化和趋势.
- 检查年龄和社会人口统计因素对这种负担的影响.
主要方法:
- 利用了2021年全球疾病负担研究 (GBD) 的数据.
- 分析了根据年龄标准化的死亡率 (ASDR) 和根据残疾调整的寿命年 (DALY).
- 使用估计年度百分比变化 (EAPC) 检查的趋势,并按地区,性别和社会人口指数 (SDI) 分层.
主要成果:
- 在全球范围内,与功能障碍相关的心血管疾病的年龄标准化死亡率和DALY率在1990年至2021年间下降 (ASDR EAPC = -1.57,DALYs EAPC = -1.44).
- 观察到显著的区域差异:澳大利亚出现了最剧烈的下降,而撒哈拉以南非洲地区出现了增长.
- 高SDI地区表现出最大的减少,而中亚和鲁在2021年表现出最高的负担率.
结论:
- 尽管全球总体下降,但功能障碍导致的心血管疾病负担在特定地区显示出有关停滞或增长的趋势.
- 人口老龄化导致持续的与年龄有关的风险,需要针对年龄的预防策略.
- 针对性干预对于高负担地区至关重要,考虑到社会人口统计学对疾病分布的影响.
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