感染大动脉旁路手术后再感染的发生率:一个元分析
Márcio Brazuna1, Marta Gonçalves-Costa2, Ana Marreiros3,4
1Faculty of Medicine and Biomedical Sience of University of Algarve, Faro, Portugal. a55054@ualg.pt.
概括
大动脉旁路移植手术后的再感染是常见的,发生率为12.7%. 高发病率和30天死亡率凸显了感染大动脉移植的标准化治疗方案的需要.
科学领域:
- 血管外科 血管外科
- 传染性疾病 传染性疾病
- 进行元分析分析.
背景情况:
- 大动脉再血管化后血管移植的感染是一种严重的并发症.
- 高发病率和死亡率与感染的大动脉旁路移植有关.
研究的目的:
- 为了确定感染大动脉旁路移植手术的患者再次感染的发生率.
- 在文献中确定与再感染相关的关键风险因素.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 在PubMed/MEDLINE,Scopus和Web of Science中搜索了2000年1月1日以后的研究.
- 进行随机效应元分析以计算聚合发病率.
主要成果:
- 包括30项涉及2341名患者的研究;整体再感染率为12.7%.
- 显著的发病率包括急性损伤 (34.1%),截肢 (23.8%),急性四肢缺血 (29.4%).
- 30天死亡率为27.8%;常见的病原体包括葡萄球菌,菌和阴性细菌.
结论:
- 受感染的大动脉旁路移植的手术治疗后,再感染率和30天死亡率很高.
- 多样化的治疗方法表明缺乏标准化的管理方案.
- 需要进一步的研究来优化手术方法,并确定患者相关的风险因素.
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