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开发针对水产养殖应用的新型宿主相关低温益生菌 (HALP)

Su-Jeong Lee¹, Young-Sun Lee¹, Yu-Ri Kim¹

¹Department of Biopharmaceutics, Dong-Eui University, Busan, 47340, Korea.

Probiotics and antimicrobial proteins

|November 8, 2025

概括

研究人员开发了用于水产养殖的新型宿主相关低温益生菌 (HALP). 这些益生菌增强了鱼类的生长,免疫力和肠道健康,显示了可持续水产养殖实践的前景.

科学领域:

水产养殖是水产养殖的一种方式.
微生物学微生物学
免疫学免疫学免疫学

背景情况:

水产养殖的成功取决于在不同温度下有效的益生菌.
开发适应温度的益生菌对于鱼类的健康和生长至关重要.

研究的目的:

开发和评估用于水产养殖的与宿主相关的低温益生菌 (HALP).
评估韩国岩鱼中三种细菌菌株的安全性,体外特征和体内疗效.

主要方法:

从韩国岩石鱼中分离和鉴定了三种细菌菌株 (Rahnella inusitata,Pseudoalteromonas arctica,Lactiplantibacillus plantarum) 的细菌.
在体外测试安全性 (血液溶解/细胞毒性活性),益生菌潜力 (抗氧化剂,耐受性,抗微生物,粘附性) 和体内养试验.
分析鱼类生长参数,免疫标记,基因表达和肠道微生物群组成.

主要成果:

这三种菌株都是安全的,并显示出益生菌的潜力.
R. inusitata (RI) 增强了天生的免疫力和免疫基因表达.
P. arctica (PA) 改善了生长速度和消化酶活性.
L. plantarum (LP) 刺激了免疫反应,改变了肠道微生物群的多样性,并增加了有益细菌.

结论:

每个HALP菌株对水产养殖都有独特的好处.
这些发现支持使用适应温度的益生菌来增强鱼类健康和水产养殖的可持续性.
对优化益生菌组合的进一步研究是有必要的.

关键词:

水产养殖是水产养殖的一种方式.与宿主相关的低温益生菌.微生物群中的微生物群益生菌益生菌是一种益生菌.岩石鱼是一种岩石鱼.

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