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Updated: Jan 12, 2026

Characterization of Synthetic Polymers via Matrix Assisted Laser Desorption Ionization Time of Flight MALDI-TOF Mass Spectrometry
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Characterization of Synthetic Polymers via Matrix Assisted Laser Desorption Ionization Time of Flight MALDI-TOF Mass Spectrometry

Published on: June 10, 2018

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从反应能量学到自动化分析工具辅助识别:一种自我验证的多维液体染色学和质谱学框架,用于对卡巴胺抗生素中的聚合杂质进行表征

Fan Wang1, Rongkang Mu2, Xin Chen2

  • 1Zhejiang Institute for Food and Drug Control, Key Laboratory for Core Technology of Generic Drug Evaluation National Medical Product Administration & Key Laboratory of Drug Contacting Materials Quality Control of Zhejiang Province, Hangzhou, 310052, China; Faculty of Medicine and Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

Journal of chromatography. A
|November 8, 2025
PubMed
概括

碳烯抗生素中的聚合杂质是一个公共卫生问题. 这项研究开发了一种新的分析策略,以识别和描述这些杂质,揭示它们的形成机制并帮助药物安全.

关键词:
2D HPSEC×LC-Q-Exactive MS 在 2D HPSEC 中使用.碳二烯的使用方法分化机制的分化机制.在 HPSEC 中,聚合杂质杂质的多重化.理论上的计算理论上的计算.在UHPLC-Q-TOFMSMS中使用.

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