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Updated: Jan 12, 2026

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针对FXR的药物发现:最近的进展和治疗前景

Qian Li1, Zihang Liu1, Weidong Shang2

  • 1School of Life Science and Engineering Southwest Jiaotong University, Chengdu, Sichuan, 610031, China.

European journal of medicinal chemistry
|November 8, 2025
PubMed
概括

法内索伊德X受体 (FXR) 调节关键的代谢过程,是胆酸疾病的有希望的标. 药物化学的近期进展导致了几种FXR激动剂的开发,更多的在临床试验中.

关键词:
激进主义者的激进主义者设计策略 设计策略在 FXR 和 FXR 之间.结构修改是指结构的修改.结构与活动的关系.

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