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Updated: Jan 11, 2026

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在Yarrowia lipolytica中,设计的非正规的还原性TCA通路驱动了高产酸生物合成

Huilin Tao1, Aomei Hao1, Xiaoyue Pan1

  • 1State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, PR China.

Metabolic engineering
|November 8, 2025
PubMed
概括

我们在酵母中设计了一种新的非正规的还原性TCA通路,以克服酸 (SA) 生产中的氧化还原限制. 这种方法显著提高了从葡萄糖,基纤维素解液和甘油中获得的SA产量.

关键词:
非正规的rTCA路径氧化还原失衡是指还原失衡.减少型TCA循环的减少型TCA循环葡萄糖酸生物合成的生物合成雅罗维亚 (Yarrowia lipolytica) 是一个高脂的植物.

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