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Updated: Jan 11, 2026

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鉴定一种新的p65-p68循环:在瘤发生过程中对p68基因调节的关键决定因素

Mrinal K Ghosh1, Sunny Kumar1, Veenita Khare1

  • 1Cancer Biology and Inflammatory Disorder Division, Council of Scientific and Industrial Research-Indian Institute of Chemical Biology (CSIR-IICB), TRUE Campus, CN-6, Sector-V, Salt Lake, Kolkata-700091 & 4, Raja S.C. Mullick Road, Jadavpur, Kolkata, 700032, India.; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh, 201 002, India.

Biochimica et biophysica acta. Gene regulatory mechanisms
|November 8, 2025
PubMed
概括

在RelA (p65) 和DEAD-boxRNA酶DDX5 (p68) 之间的新的反循环驱动着结直肠癌和质瘤的癌症生长. 抑制这种"p65-p68循环"抑制了瘤的进展,突出了它的治疗潜力.

关键词:
在 ChIP-seqq.结肠直肠癌是一种癌症.在DDX5 (p68) 中.基因调节 基因调节质瘤是一种质瘤.这种NF-κB (RelA/p65) 基因.瘤发生的发生因子.

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