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Updated: Jan 11, 2026

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
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Published on: September 19, 2017

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DNA的稳定性和展开:RNA杂交G-四重复合体

Bo Zhang1, Si-Lan Li1, Xiao Zhu1

  • 1College of Basic Medicine, Zunyi Medical University, Zunyi, China.

Nucleic acids research
|November 8, 2025
PubMed
概括

研究人员开发了一种新方法来创建统一的DNA:RNA杂交G-四复合体 (hG4s). 他们发现,增加RNA含量增强了hG4的稳定性,并确定了结合和解这些结构的蛋白质,为细胞调节提供了洞察力.

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A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase111:25

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1

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