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Updated: Jan 11, 2026

Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
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通过点击化学开发可编程RNA成像与RNA引导的GFP

Jun Nakamura1, Miyako Shiraishi2,3, Junpei Yamamoto2

  • 1Graduate School of Frontier Bioscience, The University of Osaka, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan.

Nucleic acids research
|November 8, 2025
PubMed
概括

研究人员创建了RNA引导的绿色光蛋白 (RGG),这是一种用于精确准和可视化活细胞中核酸的新型系统. 这种RNA成像平台提供了一个可编程和高效的分子分析方法.

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相关概念视频

Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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