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前额前环Homer1调节可卡因诱导的突触和行为适应

Yun Chen1,2, Zhongyu Zhang1, Xianfeng Li3

  • 1National Institute on Drug Dependence and Beijing Key Laboratory on Drug Dependence Research, Peking University, Beijing, 100191, China.

Molecular psychiatry
|November 8, 2025
PubMed
概括

循环RNAs (circRNAs),特别是circHomer1,在物质使用障碍 (SUD) 中发挥着关键作用. 大脑中较低的circHomer1水平增加了可卡因奖励,这表明circHomer1是成治疗的潜在目标.

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