在棕植物性牛皮和牛皮关节炎的心理并发症:一个系统的审查
Katya Peri1, Ebiuwa Alicia Ibude2, Jennifer V H Tran3
1Faculty of Medicine, McGill University, Montreal, QC, Canada.
Journal of cutaneous medicine and surgery
|November 9, 2025
概括
抑郁症和焦虑症等心理问题在牛皮关节炎 (PsA) 和棕叶牛皮 (PPP) 中很常见. 在这些牛皮患者中,较高的疾病活性与更严重的精神健康状况相关.
科学领域:
- 皮肤病学和精神病学
- 慢性炎症疾病 慢性炎症疾病
- 心理相关疾病 心理相关疾病
背景情况:
- 牛皮是一种慢性炎症性皮肤疾病.
- 心理并发症在牛皮中很常见,但在非斑块亚型中研究较少.
- 专注于关节性,红皮性,性和棕植物性牛皮 (PPP).
研究的目的:
- 对研究较少的牛皮变种的心理并发症进行审查.
- 文献搜索侧重于PPP和牛皮关节炎 (PsA).
主要方法:
- 在Medline,Embase,PsycINFO和PubMed的综合文献搜索,截至2025年2月.
- 提取心理相关疾病,疾病严重程度和人口统计数据.
- 包括17项研究,涉及76567名PPP和/或PSA患者.
主要成果:
- 在PsA中抑郁症的患病率:7.1%-41%;在PPP中:5.7%-17.1%.
- 焦虑的发生率:5.1%-61.4%.
- 较高的疾病活动与更严重的抑郁和焦虑有关;抑郁患者报告更高的疾病严重程度的可能性>4倍 (AOR:4.43).
- 其他并发症:睡眠障碍 (38%),PPP中的情绪障碍 (19.6%).
- 功能障碍:轻度至中度;疼痛评估显示中度不适.
结论:
- 在非斑块性牛皮症中,心理并发症的证据仅限于PsA和PPP.
- PsA和PPP与抑郁症和焦虑症的风险增加有关.
- 强调需要在这些人群中进行心理健康查和管理.
- 对于其他非斑块性牛皮的亚型需要进一步研究.
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