复发体积与左心室体积比率对心室功能性 mitra 复发的预后影响
Masafumi Yoshikawa1, Hisao Otsuki1, Takanori Kawamoto1
1Department of Cardiology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
European heart journal. Cardiovascular Imaging
|November 9, 2025
概括
额叶回体积与左心房体积 (RVol/LAV) 的比率可以预测心力衰竭住院后的心脏管边缘到边缘修复室内功能性额叶回. 较低的RVol/LAV比率表明风险更高,这表明它在患者风险分层中的有用性.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 干预心脏病学 干预心脏病学
背景情况:
- 腹腔功能性 mitra 反 (VFMR) 是一个重大的临床挑战.
- 跨导管边缘到边缘修复 (M-TEER) 是VFMR的一种成熟治疗方法.
- 在接受M-TEER的VFMR患者中,回体积 (RVol) 与左心房体积 (LAV) 的比例的预后值尚不清楚.
研究的目的:
- 调查RVol/LAV比率与VFMR患者的临床结果之间的关联.
- 为了确定RVol/LAV比率是否可以改善M-TEER患者的风险分层.
主要方法:
- 分析了1830名为VFMR接受M-TEER的患者的多中心前性注册表.
- RVol/LAV比率是从基线跨胸腔心声图计算出来的.
- 患者被分为低 (RVol/LAV <0.40) 和高 (RVol/LAV ≥0.40) 的RVol/LAV比率组.
主要成果:
- 主要终点是M-TEER后三年心力衰竭住院治疗.
- 低RVol/LAV组的患者患心力衰竭住院的风险明显更高 (HR,1.25;P=0.022).
- 通过多变量考克斯回归分析,低RVol/LAV比率被确定为心力衰竭住院的独立预测因素.
结论:
- RVol/LAV比率是VFMR患者风险分层的一个有价值的指标.
- 这一比率可能有助于临床医生识别M-TEER后具有较高不良结果风险的患者.
- 进一步的研究可以探索将RVol/LAV比率纳入临床决策算法.
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