老年人听力障碍和抑郁症之间的关联:纵向分析
Malcolm P Forbes1,2, Mark W Cox2, Katharine Brewster3
1The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, Victoria, Australia.
概括
中度至重度听力损失 (HL) 在老年人中显著增加抑郁症的风险. 助听器的使用可以大大降低这种风险,强调了听力学护理对心理健康的重要性.
科学领域:
- 老年学是指老年学的学科.
- 听力学 听力学是指听力学.
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 听力损失 (HL) 在老年人中普遍存在,并与不良健康结果有关.
- 关于听力障碍和抑郁症的现有研究往往是横截面的,限制了对纵向关联的理解.
- 助听器在减轻听力损失患者抑郁风险中的作用需要进一步调查.
研究的目的:
- 为了研究听力和老年人的抑郁事件的纵向,时间变化的听力测量测量之间的联系.
- 评估助听器的使用是否会随着时间的推移改变听力状况和抑郁症之间的关联,在中度至重度HL患者中.
主要方法:
- 包括1260名参与者在基线,18个月和36个月进行纯色调听力测试.
- 使用CES-D-10尺度 (切割分数≥8) 评估抑郁症.
- 考克斯的比例危险分析检查了听力状态 (正常,轻度,中度/重度HL) 和抑郁症之间的联系,并对共变量进行了调整.
主要成果:
- 与正常听力相比,患有中度至重度HL的参与者表现出发生抑郁症的风险明显更高 (调整HR:1.24;P<0.01).
- 在中度至重度HL患者中,助听器使用 (≥6小时/天) 与发生抑郁症的风险显著降低有关 (调整HR:0.65;P<0.01).
- 随访时间的中位数为7.3年.
结论:
- 中度至严重的听力损失是老年人患抑郁症的重要危险因素.
- 助听器的使用有效地减轻了与中度至重度听力损失相关的抑郁症风险增加.
- 需要进一步的研究来探索连接听力损失和情绪障碍的机制性途径.
相关概念视频
Long-term Depression
33.0K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.0K
Long-term Depression
3.0K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
Calcium Ion Concentration Mechanism
If over...
3.0K
Depressive Disorders: Etiology
406
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
406
Depression: Overview
735
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
735
Longitudinal Research
13.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.0K
Depressive Disorders: MDD and Dysthymia
547
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
547


