HoloFoodR:一个统计编程框架,用于整体经济数据集成工作流程
Tuomas Borman1, Artur Sannikov2, Robert D Finn3
1Department of Computing, University of Turku, Turku 20014, Finland.
Bioinformatics (Oxford, England)
|November 9, 2025
概括
Holo-omics集成宿主和微生物组数据进行相互作用研究. 一个新的R包,HoloFoodR,桥梁数据资源和分析工具,使得可重复的研究工作流在这个新兴领域.
科学领域:
- 微生物组研究 微生物组研究
- 系统生物学 系统生物学
- 生物信息学是一种生物信息学.
背景情况:
- 整体化学集成了来自宿主生物及其微生物组的多原子数据集.
- 像HoloFood这样的精心策划的,开放的全原子数据库正在出现.
- 在全原子数据资源和分析框架之间存在差距.
研究的目的:
- 为应对整合全原子数据资源与算法框架的挑战.
- 促进设计的开放和可重复的研究工作流程在全体经济学.
主要方法:
- 开发了HoloFoodR R/生物导体套件的开发.
- 利用统计编程与精心策划的全原子数据集.
- 使用HoloFood数据库,其中包含大约10,000个鱼和肉的全原子概况.
主要成果:
- 该HoloFoodR包提供了一个算法框架,用于全原子数据分析.
- 能够整合多原子数据集用于宿主微生物群相互作用研究.
- 通过开源代码和精选数据,促进可重现的研究.
结论:
- 将统计编程的进步与精心策划的全原子数据相结合,可以实现开放和可重复的工作流.
- HoloFoodR增强了全原子数据库在科学研究中的实用性.
- 这项工作支持新兴的全体经济学领域的进步.
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