DASH图案杂货和对血压的影响:GoFresh随机临床试验
Stephen P Juraschek1,2,3, Hannah Col1, Kayla Ferro1
1Division of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
JAMA
|November 9, 2025
概括
在黑人成年人中降低血压 (BP) 和LDL胆固醇. 然而,在干预结束后,这些健康改善并没有持续.
科学领域:
- 心血管健康
- 营养科学
- 公共卫生干预措施
背景情况:
- 在控制的环境下,饮食方法阻止高血压 (DASH) 的饮食计划有效降低血压.
- 通过实用的杂货战略将DASH的好处转化为社区环境仍然是一个挑战,特别是在健康食品选择有限的城市地区的黑人成年人.
研究的目的:
- 在波士顿的黑人居民中评估低的DASH样式杂货对心压的影响.
- 对比提供DASH杂货和营养师咨询的效果与自我指导的杂货购物的财务激励.
主要方法:
- 一个平行组随机临床试验, 涉及波士顿180名黑人成人,
- 参与者可以获得12周的家庭送达DASH杂货和营养师咨询,或者每4周一次获得500美元的自主购物津贴.
- 主要结论是静脉血压的变化;次要结论包括静脉血压,BMI,HbA1c和LDL胆固醇. 通过24小时尿液中的分泌量来测量粘附性.
主要成果:
- 与自我指导组 (-2.3 mm Hg) 相比,使用DASH模式的杂货组的静脉压下降幅度明显更大.
- DASH组也显示了腹压,尿液度和LDL胆固醇的显著降低.
- 没有观察到BMI或血红蛋白A1c水平的显著变化. 干预后6个月没有维持观察到的益处.
结论:
- 家庭送达的DASH杂货与饮食师的支持可以有效降低黑人成年人的血压和LDL胆固醇,
- 这项研究强调了定制杂货干预的潜力, 但强调了长期坚持和维持健康益处的挑战.
- 需要进一步的研究来制定可持续的策略,以维持社区饮食干预措施的积极效果.
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