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Updated: Jan 11, 2026

Oropharyngeal Administration of Bleomycin in the Murine Model of Pulmonary Fibrosis
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Oropharyngeal Administration of Bleomycin in the Murine Model of Pulmonary Fibrosis

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皮尔芬尼治疗二级和三级辐射引起的肺损伤:一个多中心,开放标签,随机化,第二阶段试验

Zan Hou1, Baiqiang Dong1, Qiwei Yao2

  • 1Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China; United Laboratory of Frontier Radiotherapy Technology of Sun Yat-sen University & Chinese Academy of Sciences Ion Medical Technology Co, Ltd, Guangzhou, China.

The Lancet. Oncology
|November 9, 2025
PubMed
概括

皮尔芬尼与葡萄糖皮质类药物结合,改善了辐射引起的肺损伤患者的肺功能. 这种抗纤维化疗法为胸部放射治疗后的肺损伤提供了潜在的治疗方法.

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Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
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Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
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Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
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Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists

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