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图像特征与头骨MRgFUS的结果相关 - - 一个系统的审查

Fengting Wang¹, Kuanghao Ye¹, Halimureti Paerhati²

¹Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China; Center for Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

|November 9, 2025

概括

磁共振引导聚焦超声波 (MRgFUS) 的结果取决于病变的大小和位置. 脑成像生物标志物,包括病变特征和连接性,预测治疗成功的基本震,帕金森病和精神疾病.

科学领域:

神经学神经学
神经外科神经外科
放射学放射学是一门学科.

背景情况:

对MRgFUS结果的成像相关的研究正在增长,但缺乏跨不同患者群体的全面合成.
了解成像生物标志物对于优化MRgFUS疗效和安全至关重要.

研究的目的:

系统地审查与MRgFUS治疗结果相关的技术特定的成像生物标志物.
为了分析这些生物标志物,跨越基本震,帕金森病和精神疾病.

主要方法:

对研究MRgFUS结果的系统文献综述.
分析成像数据,包括病变特征和大脑连接 (DTI,rs-fMRI).

主要成果:

对于基本震,较大的Vim病变交叉DRTT与更好的震减缓相关,但不良事件风险更高.
扩散张力成像和rs-fMRI显示治疗后白质重塑和功能网络恢复.
帕金森病的结果取决于STN或Vim内的切除特异性,而治疗前的连接性可以预测反应.
精神疾病的有限数据表明,损伤向和连接性影响结果.

结论:

损伤特征和大脑连接是优化MRgFUS策略的关键因素.
影像生物标志物对于预测和增强神经和精神疾病的MRgFUS治疗成功至关重要.

关键词:

生物标志物生物标志物基本的震震.磁共振引导的聚焦超声波是指导的.神经成像是一种神经成像.帕金森病是帕金森氏症的一种疾病.

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