河马酶MST1/2整合了无菌和传染信号,以调节巨细胞死亡

Sydney M Quagliato1, Matthew Gulker1, Ryan Mirhosiny1

  • 1Department of Biological Sciences, College of Liberal Arts and Sciences, Wayne State University, Detroit, Michigan, USA.

概括

哺乳动物STE20类酶MST1/2 (河马酶) 在巨细胞中被分裂,以控制感染期间的细胞死亡. 这种裂变协调了亡和热亡,对于宿主对病原体的防御至关重要.

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