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Updated: Jan 11, 2026

Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins
08:39

Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins

Published on: May 22, 2017

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稳定离子选择性纠正通道rhodopsins中的激活漂移

Xiao Duan1, Chong Zhang1, Stanislav Ott2

  • 1Department of Neurophysiology, Institute of Physiology, University Wuerzburg, 97070, Wuerzburg, Germany.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|November 10, 2025
PubMed
概括

新的KCR1-C29D光遗传工具通过保持选择性,可靠地使神经元沉默,与其他变体不同. 这一突破提供了跨物种和条件的稳定,有效的神经电路抑制.

关键词:
通道罗多普辛 (KCR) 是一种通道罗多普辛.脱极化和超极化两种情况.神经元激活的过程这是神经元抑制.视觉遗传学 视觉遗传学

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