发育第6至第13周的人类肌肉的形态发生:解剖学方面和临床功能相关性
Elena Martínez-Sanz1,2, Mª Carmen Barrio-Asensio2,3, Estela Maldonado1,2
1Departamento de Anatomía y Embriología, Facultad de Medicina, Universidad Complutense de Madrid (UCM), Madrid, Spain.
概括
这项研究详细介绍了人类肌的胚胎发育过程,揭示了它们起源于宫体和早期结构组织. 了解这种形态发生,可以澄清部和呼吸中的解剖变异和功能作用.
科学领域:
- 胚胎学 胚胎学
- 人体解剖学 解剖学 解剖学
- 历史学 历史学 历史学
背景情况:
- 部肌肉对于宫解剖学和功能至关重要.
- 目前关于它们早期发育的研究是有限的.
研究的目的:
- 为了研究人类骨肌肉的胚胎和胎儿形态发生.
- 阐明肌的发育起源和早期结构组织.
主要方法:
- 分析33个人类胚胎和胎儿 (6-13周),使用序列组织学切口.
- 传统的光显微镜检查组织发育.
主要成果:
- 到第6周,状母细胞形成,分化为前骨和中骨.
- 腕和关节下动脉影响胚芽细胞的细分.
- 在10.6%的标本中观察到 scalenus minimus 肌肉.
- 推测出源于宫体 (hypaxial myotomes 和 sclerotomes) 的起源.
结论:
- 状肌肉从部索米特发育,早期细分受邻近的神经血管结构的影响.
- 这种发育过程可以解释临床解剖学变异.
- 前的胸腔插入为呼吸机制提供了洞察力.
相关概念视频
Gastrulation
65.9K
Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
65.9K
Bone Formation by Intramembranous Ossification
10.1K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
10.1K
Muscles that Move the Head
5.5K
The muscles that move the head are a dynamic and complex group of structures that work together to facilitate a wide range of head movements, including rotation, flexion, extension, and lateral bending.
The bilateral sternocleidomastoid, or SCM, and the suprahyoid and infrahyoid muscles are significant head flexors. The SCM muscles originate at the sternum and clavicle and attach to the mastoid process of the temporal bone. The SCM contracts bilaterally to bend the head forward, whereas...
The bilateral sternocleidomastoid, or SCM, and the suprahyoid and infrahyoid muscles are significant head flexors. The SCM muscles originate at the sternum and clavicle and attach to the mastoid process of the temporal bone. The SCM contracts bilaterally to bend the head forward, whereas...
5.5K
Changes in the Appendicular Skeleton with Age
3.3K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
3.3K
Sutures of the Skull
10.0K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
10.0K
Muscles of the Shoulder
8.6K
The muscles surrounding the shoulder girdle, including the clavicle and scapula, primarily stabilize the scapula. This stable base allows other muscles to move the humerus effectively. Scapular movements often mirror those of the humerus and extend its range of motion. For instance, raising the arm above the head would not be feasible without simultaneous upward rotation of the scapula.
Anterior Thoracic Muscles
The anterior thoracic muscles include the serratus anterior, subclavius, and...
Anterior Thoracic Muscles
The anterior thoracic muscles include the serratus anterior, subclavius, and...
8.6K


