估计抑郁症推心理治疗的最小值得差异:观察性研究
Ethan Sahker1,2, Yan Luo1,2, Kenji Omae2,3
1Population Health and Policy Research Unit, Center for Medical Education and Internationalization, https://ror.org/02kpeqv85Graduate School of Medicine, Kyoto University, Kyoto, Japan.
The British journal of psychiatry : the journal of mental science
|November 10, 2025
概括
抑郁症心理治疗的最小值得的差异 (SWD) 是响应率的20%差异,类似于抗抑郁药. 患者的偏好对于治疗决策至关重要.
科学领域:
- 心理健康研究 心理健康研究
- 临床心理学 临床心理学
- 心理治疗的有效性 心理治疗的有效性
背景情况:
- 最小值得的差异 (SWD) 是了解患者感知干预价值的关键.
- 之前的SWD估计存在于抗抑郁药物,但没有用于抑郁症的心理治疗.
研究的目的:
- 为了估计对抑郁症推心理治疗的SWD,与没有治疗相比.
- 为了比较心理治疗的SWD与抗抑郁药物的SWD.
主要方法:
- 2个月后通过患者所需的响应率差异 (心理治疗与不治疗) 估计的SWD.
- 通过Prolific在2025年1月在英国和美国进行的在线横截面调查.
- 复制之前对抗抑郁药物的SWD估计,使用受访者的子集.
主要成果:
- 对于中度至重度抑郁症 (未接受治疗) 的中位数SWD是20%的响应率差异 (IQR:10-35%).
- 这种SWD与抗抑郁药物的SWD相似 (SWD=20%,IQR:10-30%).
- 参与者特征没有显著影响SWD.
结论:
- 目前的心理治疗反应率 (15%) 对于三分之二的患者来说是不够的,他们希望获得更大的好处或减少负担.
- 心理治疗的SWD与抗抑郁药的SWD没有很大不同.
- 需要更加关注个体患者的价值和偏好;建议进行多样化的样本复制.
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