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Updated: Jan 11, 2026

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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PI3K/Akt/mTOR路径:在IR/MASH相关的肝细胞癌中免疫代谢编排

Jian Zhao1, Yuehua Zhang2, Zhigong Wei3

  • 1Thoracic Oncology Ward, Cancer Center, and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, P.R. China.

International journal of biological sciences
|November 10, 2025
PubMed
概括

胰岛素耐药性和与代谢功能障碍相关的胆固醇肝炎通过重新编程PI3K/Akt/mTOR途径来驱动肝癌. 这种重新连接创造了一个免疫抑制的瘤微环境,为肝细胞癌提供了新的治疗点.

关键词:
肝细胞癌 肝细胞癌胰岛素耐药性 胰岛素耐药性是一种马什 (MASH) 是一个非常重要的产品.代谢重编程 代谢重编程在PI3K/Akt/mTOR信号通路中.瘤 免疫 微环境

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