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Updated: Jul 19, 2026

Isolation and Enrichment of Human Lung Epithelial Progenitor Cells for Organoid Culture
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人类多能干细胞衍生膜器官用于基因编辑和肺腺癌模型

Lian Li1, Yuchen Liu1, Lifan Liu1

  • 1Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangdong Province Key Laboratory of Immune Regulation and Immunotherapy, Southern Medical University, Guangzhou 510515, China.

International journal of biological sciences
|November 10, 2025
PubMed
概括

我们为肺部研究开发了人类多能干细胞衍生膜器官 (hALO). 这种精简的系统提供了长期扩展和疾病建模能力,推进了肺部发育和疾病研究.

关键词:
带膜体内有机物基因工程是基因工程,是基因工程.长期可扩展性的长期可扩展性肺部腺癌的癌症.

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Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...