在重症监护病房实施选择性消化器消毒协议的影响
Rosario Fernández-Fernández1, Eugenia Yuste-Ossorio1, Natalia Chueca-García1
1Hospital Universitario San Cecilio, Granada, Spain.
概括
选择性消化道去污染 (SDD) 减少了重症患者的导管相关血流感染. 这种抗微生物策略没有增加多抗药生物体的殖民化,在重症监护病房提供了潜在的好处.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 医院流行病学 医院流行病学
背景情况:
- 在重症监护室 (ICU) 使用选择性消化道去污染 (SDD) 是有争议的.
- 抗菌素耐药性是一个日益关注的问题,受患者和ICU因素的影响.
研究的目的:
- 评估SDD协议对医院感染和多药耐药生物体 (MDRO) 在ICU中的殖民的影响.
主要方法:
- 一项前性观察性研究比较了在机械通风患者中SDD实施前两年和之后的两年.
- 计算了感染的发病率密度率和与设备相关的感染.
- 微生物监测跟踪了MDRO入院时和每周的殖民化.
主要成果:
- 导管相关的血液感染在SDD后显著减少 (RR:0.157,p=0.006).
- 总体感染率显示没有显著下降 (RR:0.71,p=0.16).
- MDRO殖民率也下降,但没有显著下降 (3.26%对2.36%).
结论:
- 实施SDD导致了与导管相关的血液感染的显著减少.
- 这项研究发现,与SDD相关的MDRO殖民地没有增加.
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