HBHA-ECSIT,Mycobacterium

Yongqiang Li1, Xiuping Jia2, Xiaoying Wang2

  • 1Department of Clinical Laboratory, Air Force Medical Center, Beijing, China.

Frontiers in immunology
|November 10, 2025
PubMed
概括

结核菌菌 (Mtb) 使用其毒性因子 - - 肝素结合性血凝素 (HBHA) 来向宿主蛋白 ECSIT,阻断自并促进潜伏结核病感染 (LTBI) 中的细菌持久性. 这种HBHA-ECSIT相互作用对于Mtb生存至关重要.

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