来自牛的异基酸改善了断奶小猪的抗氧化能力,免疫功能和肠道微生物群
Yuxin Wang1, Yong Luo2, Honglei Zou1
1Key Laboratory of Animal Disease-Resistant Nutrition, Ministry of Education, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China.
Frontiers in veterinary science
|November 10, 2025
概括
饮食中服用异基酸 (ICGA) 补充剂改善了断奶小猪的生长,营养消化能力和肠道健康. ICGA增强了抗氧化剂状态,免疫功能和有益的肠道细菌,同时减少了腹的发生率.
科学领域:
- 动物营养 动物营养
- 兽医科学 兽医科学 兽医科学
- 微生物学 微生物学
背景情况:
- 单酸 (ICGA) 是一种植物衍生的化合物,具有已知的抗氧化,抗菌和抗炎性质.
- 断奶是小猪的关键时期,通常与生长减缓,消化问题和肠道微生物群的改变有关.
- 研究了食补充的策略,以减轻断奶后的挑战,并改善小猪的健康和表现.
研究的目的:
- 评估饮食中含有异基酸 (ICGA) 补充剂对断奶小猪生长表现,腹发病率,抗氧化状态,免疫功能和肠道微生物群的影响.
- 在小猪模型中确定ICGA的最佳剂量以获得有益效果.
主要方法:
- 180只杂交品种的猪仔被养了补充了0,100,200,400或800毫克/公斤ICGA的饮食,持续了28天.
- 评估了生长性能 (平均每日增益 - ADG),营养物的明显全管消化能力 (ATTD),血清抗氧化酶活性 (catalase - CAT,总抗氧化能力 - T-AOC),免疫球蛋白水平 (IgA,IgM) 和肠道微生物群组成.
- 进行了统计分析,以确定治疗组之间的显著差异.
主要成果:
- 补充200mg/kgICGA在15-28日期间显著增加了ADG.
- 200和400毫克/公斤ICGA的饮食改善了干物质,原蛋白,总能量,提取物和灰的ATTD.
- ICGA增强了血清CAT活性和T-AOC,提高了IgA和IgM水平,增加了有益细菌 (Bacteroidota,Prevotella),并减少了致病细菌 (Peptostreptococcaceae,Proteobacteria,Staphylococcus).
结论:
- 食ICGA补充剂在200-400mg/kg的剂量是有效的改善成长性能,营养消化,抗氧化能力和免疫功能在断奶的小猪.
- ICGA积极调节肠道微生物群,减少腹的发生率,促进更健康的肠道环境.
- 建议进行进一步的研究,以探索ICGA在猪生产中的作用机制和实际应用.
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