一位患有性综合征的老年CABG患者的抗血栓管理:一个病例报告
Feng Xu1, Liu-Cheng Li2, Miao-Miao Chen2
1Department of Pharmacy, Ningbo No. 2 Hospital, Ningbo, China.
Frontiers in cardiovascular medicine
|November 10, 2025
概括
血小板结晶学 (TEG) 在复杂冠状动脉旁路移植 (CABG) 患者中有效指导双重抗血小板治疗 (DAPT) 和抗凝剂的使用. 这种方法优化了凝血,最大限度地降低了出血风险,并在具有挑战性的病例中改善了临床结果.
科学领域:
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
- 关键护理医学 关键护理医学
背景情况:
- 对冠状动脉疾病 (CAD) 的冠状动脉旁路移植 (CABG) 具有显著的术后风险,特别是在患有脏综合征和肺部感染等并发症的老年患者中.
- 在这些高风险患者中,双重抗血小板治疗 (DAPT) 和抗凝治疗的管理是复杂的,需要精确的监测来平衡血栓形成和出血风险.
研究的目的:
- 介绍一个案例研究,证明血栓显微镜 (TEG) 的实用性,以指导接受CABG且具有重大并发症的患者的术后管理.
- 突出TEG在优化双抗血小板治疗 (DAPT) 和抗凝剂策略中发挥的作用,以减轻出血和血栓性并发症.
主要方法:
- 一名65岁的男性患者患有脏综合征和肺部感染,接受了CABG手术.
- 血小板结晶学 (TEG) 用于实时监测和指导双抗血小板治疗 (DAPT) (阿司匹林和克洛皮多格雷尔) 和抗凝剂的使用.
- 常规的凝血参数,临床评估和量身定制的抗生素治疗被整合到患者的治疗计划中.
主要成果:
- TEG有效地指导了DAPT和抗凝治疗的调整,确保了最佳的凝血状态.
- 患者经历了降至最低的出血风险和肺部感染的成功管理.
- 手术后的结局显示出稳定的凝血参数和整体临床改善.
结论:
- 血栓形成显微镜 (TEG) 是优化术后抗凝和抗血小板疗法的宝贵工具,用于复杂CABG患者的并发症.
- 将TEG整合到临床实践中可以通过尽量减少出血并发症和改善结果来提高患者的安全性.
- 包括临床药剂师在内的多学科合作对于个性化制药护理在管理高风险手术患者方面至关重要.
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