环境颗粒物的全球趋势 - 老年人中可归因的缺血性心脏病 (1990-2021年)
Yangxi Zeng1,2, Lihui Liu1,2, Gang Huang2
1Key Laboratory of Cardiovascular Remodeling and Dysfunction, Department of Cardiovascular Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Frontiers in cardiovascular medicine
|November 10, 2025
概括
空气中的颗粒物 (PM) 污染在全球范围内显著影响缺血性心脏病 (IHD),特别是在老年男性中. 虽然整体IHD负担下降,但低收入地区的弱势群体面临越来越大的风险,需要有针对性的干预措施.
科学领域:
- 环境健康 环境健康
- 心血管流行病学心血管流行病学
- 公共卫生政策 公共卫生政策
背景情况:
- 空气中的颗粒物 (PM),特别是PM2.5,对心血管健康构成重大威胁,特别是在老年人群中.
- 城市化和工业化扩大了PM2.5在缺血性心脏病 (IHD) 中的作用,这是全球主要的死亡原因.
- 细微粒子引发炎症和氧化应激,加速血管损伤,老年人特别容易受到影响.
研究的目的:
- 从1990-2021年分析PM归因于PM的IHD负担的全球,区域和国家趋势.
- 确定人口差异 (性别,年龄) 和社会经济因素对IHD负担的影响.
- 预测未来的趋势,为老龄化社会制定公共卫生战略.
主要方法:
- 使用的全球疾病负担 (GBD 2021) 死亡率和DALYs (1990-2021) 的数据.
- 计算的年龄标准化率 (ASR) 和估计的年度百分比变化 (EAPC).
- 采用贝叶斯式年龄期-队列 (BAPC) 建模用于预测,按性别和年龄分类,与PM暴露和社会经济发展相关.
主要成果:
- 总理的全球IHD负担下降,在高SDI地区减少最多;负担在亚洲和非洲低收入和中等收入地区增加.
- 与PM相关的IHD负担与社会人口统计指数 (SDI) 之间观察到负相关性.
- 男人表现出比女性更高的IHD负担,随着年龄的增长,差距越来越大;预测表明,由于未来的污染趋势,下降的速度可能会放缓.
结论:
- 尽管全球范围内的病例数量有所下降,但在东南亚和非洲,PM引起的内脏病仍然很高.
- 预计老年男性将面临不成比例地更高的PM暴露对健康的影响.
- 针对性干预以减少脆弱老年人群中的PM暴露对于减轻心血管风险和促进健康老龄化至关重要.
更多相关视频
10:11Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
Published on: October 22, 2014
19.6K
05:18Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
Published on: July 12, 2024
682
相关概念视频
01:17Ischemic Heart Disease: Overview
2.8K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
2.8K
01:30Coronary Artery Disease I: Introduction
863
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
863
01:26Coronary Artery Disease IV: Preventive Measures
578
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
578
01:30Factors Influencing Heart Rate
6.1K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
6.1K
01:15Drug Dosing: Geriatric Patients
215
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
215
01:26Coronary Artery Disease II: Pathophysiology
355
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
355