由食物蛋白引起的肠球炎引起的扩散性肠肺炎-一个病例报告
Raouf Nassar1,2,3, Keren Biham Rochwerger2,3, Ran Hazan2,3
1Pediatric Gastrointestinal Unit, Saban Children's Hospital, Soroka University Medical Center, Beer-Sheva, Israel.
AME case reports
|November 10, 2025
概括
肠道肺炎 (PI),一种肠壁中的气体状况,可以发生在满期婴儿身上. 食品蛋白诱导肠球炎综合征 (FPIES) 被确定为新生儿的罕见病因,突出了更广泛的差异诊断的需要.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 新生儿医学 新生儿医学
- 过敏和免疫学 过敏和免疫学
背景情况:
- 肠道肺炎 (PI) 是肠壁中的气体,通常与早产婴儿的死性肠球炎 (NEC) 有关.
- 孕期婴儿和年龄较大的儿童可以发生PI,其原因各异,需要广泛的差异性诊断.
- 食物蛋白诱导肠道炎综合征 (FPIES) 是一种非IgE介导的胃肠道食物过敏,通常在婴儿期出现,像PI这样的严重并发症很少见.
研究的目的:
- 报告一个罕见的PI病例在一个满期的新生儿.
- 为了调查PI的病因在一个婴儿.
- 突出FPIES作为新生儿PI的潜在原因.
主要方法:
- 一个满期的女新生儿出现吐和血的病例报告.
- 临床评估包括代谢性酸和乳酸盐升高.
- 影像研究表明扩散PI,保守的管理与肠休息和全方位肠道营养,并引入基于氨基酸的配方.
主要成果:
- 新生儿呈现出临床痛苦迹象,并且没有穿孔的扩散PI.
- 保守的管理导致临床改善和PI在后续成像中的解决.
- 一种基于氨基酸的配方被很好地容忍,没有症状的复发.
结论:
- 新生儿期以后期婴儿的PI需要广泛的差异诊断.
- 当排除其他诊断时,应该怀疑由牛奶蛋白 (CMP) 引起的食物蛋白诱导肠道炎综合征 (FPIES) 是次要的.
- 这一案例强调了FPIES是新生儿严重胃肠道表现的罕见但重要的原因,包括PI.
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