在青少年中,与抑郁症相关的智能手机语言使用的神经相关性
Elizabeth A McNeilly1, Giana I Teresi2, Saché Coury3
1Department of Psychology, University of Oregon, Eugene, OR USA.
NPP - digital psychiatry and neuroscience
|November 10, 2025
概括
青少年抑郁症与智能手机上的语言模式有关,例如增加负面词和代词使用. 这些语言标记可能反映神经认知偏见,并作为心理健康干预的潜在目标.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 数字健康数字健康
背景情况:
- 磁共振成像 (MRI) 提供了青少年抑郁症的洞察力,但缺乏可访问性.
- 开发可扩展的,基于神经科学的指标对于早期检测和治疗至关重要.
- 基于智能手机的语言分析为可访问的心理健康监测提供了潜在的途径.
研究的目的:
- 调查智能手机语言使用作为青少年抑郁症的潜在指标.
- 探索抑郁症的神经相关物是否调节或调节语言使用和抑郁症状之间的关联.
- 识别潜在干预目标在语言模式中反映的神经认知偏差.
主要方法:
- 40名患有抑郁症和没有抑郁症的青少年 (14-18岁) 接受了临床评估和休息状态fMRI扫描.
- 一个被动移动传感应用程序收集了智能手机通信中超过120万个单词的语言数据.
- 独立组件分析和双回归分析了与语言使用有关的内在大脑网络 (中央执行网络[CEN],默认模式网络[DMN],突出网络[SN]).
主要成果:
- 抑郁症与增加负面情绪词语使用和减少以未来为重点的词语使用相关.
- 更高的抑郁症状和DMN/CEN活动与更高的第一人称代名词使用有关.
- CEN连接扩大了抑郁症状和代名词使用之间的关联; SN-CEN连接调节了抑郁症和负面情绪词语之间的联系.
结论:
- 在智能手机活动中使用自然语言与青少年抑郁症有关.
- 语言模式可能反映出与抑郁相关的潜在神经认知偏见.
- 基于智能手机的语言分析为识别和潜在治疗青少年抑郁症提供了一个有希望的,易于使用的工具.
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