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Updated: Jan 11, 2026

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
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The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications

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含有2'和2'化物修饰的混合XNA聚合物的酶合成

Hailey E Kang1, Ananya Venkatesh2, Serena C Liu2

  • 1W.M. Keck Science Department, Claremont McKenna College, Claremont, California 91711, United States.

ACS omega
|November 10, 2025
PubMed
概括

具有2'azide (2'Az) 和2'fluoro (2'F) 修饰的Xeno核酸 (XNA) 可以通过XNA聚合酶合成. 一种简单的方法将这些XNA聚合物转化回DNA,为生物技术提供了多功能工具包.

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ATP and Macromolecule Synthesis01:28

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Biological macromolecules are organic compounds, predominantly composed of carbon atoms. The carbon atoms are covalently bonded with hydrogen, oxygen, nitrogen, and other minor elements. There are four major biological macromolecule classes: carbohydrates, lipids, proteins, and nucleic acids.
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Ziegler–Natta polymerization is another form of addition or chain‐growth polymerization used for synthesizing linear polymers over branched polymers. The catalyst used for polymerization is the Ziegler–Natta catalyst, named after Karl Ziegler and Giulio Natta, who developed it in 1953. This catalyst is an organometallic complex of titanium tetrachloride and triethyl aluminum, with the active form of the catalyst being an alkyl titanium compound. Using the Ziegler–Natta...
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Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
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