通过自然语言处理评估遗传咨询的效率
Michelle H Nguyen1,2, Carolyn D Applegate3, Brittney Murray4
1Institute for Computational Medicine, Johns Hopkins Whiting School of Engineering, Baltimore, MD 21218, United States.
Journal of the American Medical Informatics Association : JAMIA
|November 10, 2025
概括
自然语言处理 (NLP) 策略有效地标志着遗传咨询 (GC) 的效率和阶段性. 这种方法提供了跨专业的GC时间的真实数据,有助于未来的效率改进.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 计算语言学 计算语言学
- 遗传学 是一个遗传学.
背景情况:
- 越来越多的转诊者接受遗传咨询 (GC) 需要提高效率.
- 描述GC效率和阶段对于优化服务交付至关重要.
- 测量GC效率的现有方法在可扩展性和现实世界的适用性方面是有限的.
研究的目的:
- 开发和验证自然语言处理 (NLP) 策略,以衡量遗传咨询 (GC) 的效率.
- 根据基因测试阶段 (前或后) 将GC措施分类.
- 将NLP模型应用于大量GC笔记数据集,以在GC时间内生成真实世界的证据.
主要方法:
- 来自7个临床专业的800个GC笔记的注释,用于NLP模型开发.
- 使用NLP提取GC效率指标 (直接/间接时间,GC阶段).
- 高性能NLP模型的验证 (F1分数为时间的0.95,阶段的0.90).
- 验证模型应用于24,102个GC笔记 (2016-2023年).
主要成果:
- NLP模型在提取GC效率指标方面表现出高准确度.
- 在GC的中位直播时间为50分钟.
- 在临床专业,时间段和交付方式 (面对面与远程医疗) 之间观察到GC直接时间的显著变化.
结论:
- NLP提供了一种实用的,可扩展的策略,用于生成关于GC效率的真实世界的证据.
- 开发的NLP方法可以为提高GC效率的干预措施的研究提供信息.
- 本NLP策略的原则可能适用于其他领域的卫生服务研究.
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