HEK293

Georg Smesnik1,2,3, Nikolaus Virgolini1,2,3, Maria Toth1,2

  • 1Institute of Bioprocess Science and Engineering, Department of Biotechnology and Food Science, CD Laboratory of Knowledge-Based Production of Gene Therapy Vectors, BOKU University, Vienna, Austria.

PubMed
概括

在生物制造中使用的人类胚胎 (HEK293) 细胞保持稳定的遗传核心,尽管培养变化. 突变随着时间的推移逐渐积累,影响细胞结构基因,但不影响病毒基因整合.

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