癌症研究中的自和瘤微环境的全球图书统计视角
Ishita Debnath1, Moumita Kundu2,3
1Department of Pharmacy, Guru Nanak Institute of Pharmaceutical Science and Technology, Khardaha, West Bengal, India.
Discover oncology
|November 10, 2025
概括
自和瘤微环境 (TME) 在癌症中至关重要,影响其进展和治疗. 了解它们复杂的相互作用是开发新癌症疗法的关键.
科学领域:
- 在瘤学瘤学.
- 细胞生物学 细胞生物学
- 生物技术是生物技术.
背景情况:
- 自,一种细胞循环过程,在癌症中具有双重作用,在早期起到瘤抑制作用,但后来促进癌细胞的存活.
- 自会通过调节新陈代谢,免疫逃避和血管生成来影响瘤微环境 (TME),从而促进瘤生长和耐药性.
- 鉴于其重要的作用,自是癌症治疗的主要治疗点.
研究的目的:
- 对癌症进展中的自和瘤微环境 (TME) 的研究进行文献分析.
- 绘制协作网络的地图,并确定该领域的关键研究主题,国家和机构.
- 为未来的癌症生物学研究和治疗开发提供战略概述.
主要方法:
- 在Scopus和PubMed数据库中进行全面的文献搜索.
- 使用VOSviewer进行图书统计分析,绘制协作网络和关键字的共同出现.
- 对出版趋势和引用影响的定量分析.
主要成果:
- 关于自和癌症中的TME存在着大量且不断增长的研究 (3002篇文章).
- 中国和美国在研究成果方面处于领先地位,其中"癌症"和"瘤学的前沿"是著名的期刊.
- 主要研究主题包括自和TME在癌症诊断,预后,治疗中的作用,以及利用天然产品和药物向TME的潜力.
结论:
- 这项文献计量研究全面地绘制了癌症生物学中自和TME的交叉点.
- 确定了领先的研究人员,协作集群,知识差距以及免疫疗法和缺氧等新兴领域.
- 研究结果为未来的癌症研究方向和治疗策略提供了战略见解.
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