在单独的脏中进行尿路透镜后,功能的演变
Charles Jaouen1,2,3,4, Olivier Traxer1,2,4,5,6, Stefano Moretto1,2,4,5,7
1Endolase-GRC n°20, Groupe de Recherche Clinique sur la Lithiase Urinaire, Sorbonne University, Paris, 75020, France.
World journal of urology
|November 10, 2025
概括
灵活性尿道透视 (FURS) 对于单一脏 (SK) 的患者来说是安全的,在术后显示稳定的功能. 机器学习模型可以预测结果,帮助患者选择和预防功能障碍.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 医疗信息学 医疗信息学
背景情况:
- 灵活性尿道透视 (FURS) 在单独 (SK) 患者的安全性和功能影响方面未得到充分研究.
- 现有的文献提供了有限的证据,证实了SK患者FURS后稳定的功能.
研究的目的:
- 在SK患者的FURS后评估和预测术后功能.
- 开发和评估用于预测功能结果的机器学习 (ML) 模型.
主要方法:
- 一项双中心回顾性研究包括87名从2013年至2023年接受FURS与SK的患者.
- 收集人口统计,外科期间和功能数据 (血清肌素,eGFR).
- 训练并测试了12ML模型来预测手术后3个月的血清肌素,通过多变量分析识别风险因素.
主要成果:
- 血清肌素在3个月和长期随访时保持稳定,尽管早期的升高是暂时的.
- 确定了术后功能修改的六个预测因素,包括肠囊造形术和术前JJ支架.
- "堆叠"集团ML模型在预测术后血清肌氨酸时实现了4%的平均绝对误差,明显超过非ML预测 (17%).
结论:
- 对于孤独的脏患者来说,FURS似乎是安全的,具有可控的过渡性功能影响.
- 准确的ML预测模型可以增强患者的管理和选择,潜在地预防功能障碍.
- 对预测建模的进一步研究可以在单独的脏场景中优化FURS应用.
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