间歇性肺病的经济负担和成本驱动因素:系统性审查
Siow Yeh Chiew1, Mustapha Mohammed2, Siew Chin Ong3
1Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Pulau Pinang, Malaysia.
间歇性肺病 (ILD) 对患者和医疗保健系统产生重大影响,住院和药物费用是主要的驱动因素. 早期诊断和优化护理可以减轻ILD的经济负担.
科学领域:
- 肺部病理学 肺部病理学
- 卫生经济学 卫生经济学
- 系统审查是系统的审查.
背景情况:
- 间歇性肺病 (ILD) 包含各种亚型,包括异常性肺纤维化 (IPF) 和渐进性肺纤维化 (PPF),其特点是快速进展和不良预后.
- 最近在PPF定义和抗纤维素治疗方面的进展需要了解ILD的经济负担和成本驱动因素.
研究的目的:
- 系统地审查和总结ILD的经济负担.
- 确定患者,医疗保健系统和社会的关键成本驱动因素.
- 为了比较跨ILD亚型和地理区域的成本.
主要方法:
- 在PubMed,Scopus和Web of Science (开始至2024年1月) 的综合文献搜索.
- 包括关于ILD经济负担,疾病成本和成本效益的全长英语出版物.
- 遵守PRISMA指南和PROSPERO注册 (CRD42024504116) 的要求.
主要成果:
- 包括40项研究,揭示了大量的年度直接成本 (每名患者1593美元至177526美元) 和间接成本 (每名患者45美元至19507美元).
- 住院和药物费用是主要的成本驱动因素 (分别为40%-89%和36%-82%).
- 疾病严重程度,并发症,抗纤维素使用和区域医疗保健差异显著影响了成本.
结论:
- 间歇性肺部疾病给人带来了巨大的经济负担.
- 降低成本的策略包括早期诊断,有效管理ILD和并发症,社会支持和优化医疗保健服务.
- 解决这些因素可以改善患者的治疗结果,并减少整体经济影响.
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