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Updated: Jan 11, 2026

Isolating Malignant and Non-Malignant B Cells from lck:eGFP Zebrafish
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基于氨酸拉链的细胞分类用于净化双向量转细胞

Katerina Su1, Bintao Wang1, Adhithi Rajagopalan1

  • 1City of Hope Los Angeles and National Medical Center.

Journal of visualized experiments : JoVE
|November 10, 2025
PubMed
概括

化学抗原受体 (CAR) T细胞疗法显示出有希望的结果,但面临阻力. 这项研究引入了一种新的双向量转导和分类方法,以增强癌症治疗的CAR T细胞治疗.

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Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
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