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相关概念视频

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...

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相关实验视频

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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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Published on: March 6, 2018

前列腺癌,版本3.2026,NCCN瘤学临床实践指南.

Daniel E Spratt1, Sandy Srinivas2, Nabil Adra3

  • 11Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.

Journal of the National Comprehensive Cancer Network : JNCCN
|November 10, 2025
PubMed
概括

该指南为前列腺癌患者提供了决策框架,详细说明了转移性割敏感 (mCSPC) 和割抵抗 (CRPC) 阶段的治疗方法. 强调共享决策,考虑患者因素和疾病特征,以获得最佳护理.

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科学领域:

  • 在瘤学瘤学.
  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科

背景情况:

  • 前列腺癌的管理需要针对不同疾病阶段的定制策略.
  • 目前的指导方针涉及转移性割敏感前列腺癌 (mCSPC) 和割抵抗性前列腺癌 (CRPC).

研究的目的:

  • 概述NCCN关于前列腺癌治疗决策的指导方针.
  • 根据疾病特征详细介绍mCSPC和CRPC的治疗方法.

主要方法:

  • 审查NCCN关于前列腺癌的指导方针.
  • 关注mCSPC和CRPC阶段的治疗考虑因素.
  • 强调共享决策原则.

主要成果:

  • 对于mCSPC的治疗决定取决于转移的时间和负担,影响治疗强化和定向治疗.
  • mCRPC管理涉及持续的雄激素剥夺疗法,添加了AR途径抑制剂,化疗,免疫疗法,放射性药物或向疗法等药物.
  • NCCN小组强调了基于患者偏好,病史,生物标志物,转移程度,症状和副作用的共享决策.

结论:

  • 美国国家前列腺癌协会指南为前列腺癌管理提供了一个全面的框架.
  • 个性化治疗策略对于mCSPC和CRPC都至关重要.
  • 共享决策是优化前列腺癌护理患者结果的重要组成部分.