前列腺癌,版本3.2026,NCCN瘤学临床实践指南
Daniel E Spratt1, Sandy Srinivas2, Nabil Adra3
11Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.
Journal of the National Comprehensive Cancer Network : JNCCN
|November 10, 2025
概括
该指南为前列腺癌患者提供了决策框架,详细说明了转移性割敏感 (mCSPC) 和割抵抗 (CRPC) 阶段的治疗方法. 强调共享决策,考虑患者因素和疾病特征,以获得最佳护理.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 前列腺癌的管理需要针对不同疾病阶段的定制策略.
- 目前的指导方针涉及转移性割敏感前列腺癌 (mCSPC) 和割抵抗性前列腺癌 (CRPC).
研究的目的:
- 概述NCCN关于前列腺癌治疗决策的指导方针.
- 根据疾病特征详细介绍mCSPC和CRPC的治疗方法.
主要方法:
- 审查NCCN关于前列腺癌的指导方针.
- 关注mCSPC和CRPC阶段的治疗考虑因素.
- 强调共享决策原则.
主要成果:
- 对于mCSPC的治疗决定取决于转移的时间和负担,影响治疗强化和定向治疗.
- mCRPC管理涉及持续的雄激素剥夺疗法,添加了AR途径抑制剂,化疗,免疫疗法,放射性药物或向疗法等药物.
- NCCN小组强调了基于患者偏好,病史,生物标志物,转移程度,症状和副作用的共享决策.
结论:
- 美国国家前列腺癌协会指南为前列腺癌管理提供了一个全面的框架.
- 个性化治疗策略对于mCSPC和CRPC都至关重要.
- 共享决策是优化前列腺癌护理患者结果的重要组成部分.
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