Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Pediatric NHP Workshop-"NHP Models for HIV Prevention and Treatment: Towards Developing Pediatric Formulations", New Orleans, LA, October 22, 2024: Summary of Proceeding-Session IV: Challenges of the Juvenile NHP Models.

Journal of medical primatology·2026
Same author

Initiation of Long-Acting Antiretroviral Combinations Achieve Sustained Virologic Remission in Early-Life SIV Infection.

Research square·2026
Same author

Metabolic reprogramming by caloric restriction enhances acute phase virological control and reduces chronic inflammation in SIV-infected rhesus macaques.

bioRxiv : the preprint server for biology·2026
Same author

A Collaborative, Multi-Institutional Growth Standard for Dam-Reared Infant Rhesus and Pigtail Macaques (Macaca mulatta and Macaca nemestrina) in Research Settings.

American journal of primatology·2026
Same author

RhCMV expands CCR5+ memory T cells and promotes SIV reservoir seeding in the gut mucosa.

JCI insight·2025
Same author

<i>Aliarcobacter butzleri</i> colitis in rhesus macaques (<i>Macaca mulatta</i>).

Veterinary pathology·2025

相关实验视频

Updated: Jan 11, 2026

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
06:59

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

Published on: November 13, 2016

11.4K

在 rhesus macaques (Macaca mulatta) 中确定A1C正常值

Jason P Dufour1, Lara Doyle-Meyers1, Kathrine Falkenstein1

  • 1Tulane National Primate Research Center, Covington, Louisiana.

Journal of the American Association for Laboratory Animal Science : JAALAS
|November 10, 2025
PubMed
概括

研究人员在 rhesus macaques 中确定了正常的糖化血红蛋白 (A1C) 范围,这对糖尿病研究至关重要. 这项研究发现男性的A1C水平较高,为2型糖尿病的非人类灵长类动物模型提供了重要的参考.

关键词:
A1C,含糖血红素的血红蛋白.BCS,身体状况得分,身体状况得分.NHP,非人类灵长类动物.T2DM,第二种类型糖尿病.TNPRC,图兰国家灵长类动物研究中心.

更多相关视频

Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques
07:11

Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques

Published on: April 22, 2010

21.7K
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

25.0K

相关实验视频

Last Updated: Jan 11, 2026

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
06:59

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

Published on: November 13, 2016

11.4K
Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques
07:11

Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques

Published on: April 22, 2010

21.7K
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

25.0K

科学领域:

  • 比較醫學是比較醫學.
  • 内分泌学 在内分泌学.
  • 灵长类动物研究研究

背景情况:

  • 2型糖尿病 (T2DM) 是一个日益严重的全球健康问题.
  • 非人类灵长类动物 (NHPs),特别是 rhesus macaques,由于与人类的生理相似性,是T2DM研究的重要模型.
  • 确定关键代谢标记物如糖化血红蛋白 (A1C) 的特定物种的正常范围对于准确的研究至关重要.

研究的目的:

  • 在健康的成年 rhesus macaques (Macaca mulatta) 中确定糖化血红蛋白 (A1C) 的正常范围.
  • 为未来的糖尿病研究在本NHP模型中建立A1C水平的可靠参考标准.
  • 在 rhesus macaques 中调查 A1C,血糖,年龄,体重和性别之间的潜在相关性.

主要方法:

  • 收集了210只健康,不肥胖的印度 rhesus (年龄为5-10岁) 的血液样本.
  • 使用A1CNow+套件测量A1C,并通过医疗中心的血糖计和实验室分析测量血糖.
  • 使用了统计分析,包括沙皮罗-威尔克斯测试,回归和R的相关系数.

主要成果:

  • 在健康的成年 rhesus macaques 中,A1C 的平均值为 5.92% (范围: 4.4%-9.9%).
  • 与雌性 (5.69%) (P=0.004) 相比,雄性的平均A1C水平显著更高 (6.07%) (P=0.004).
  • 在A1C和血糖,体重,身体状况得分或年龄之间没有发现显著的相关性,尽管在排除异常值时,性别和体重显示出相互作用.

结论:

  • 这项研究确定了健康成年 rhesus macaques 中A1C 的第一个全面参考范围.
  • 确定的正常A1C值高于以前报告的NHP和人类标准.
  • 这些发现对于利用 rhesus macaques作为模型推进T2DM研究至关重要,提高了对NHP和人类群体疾病的理解.