天然多糖化合物 调节冰核通过充电
Yunhe Diao1, Beili Huang1, Kaiyong Li2
1School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China.
Biomacromolecules
|November 10, 2025
概括
高负电荷的多糖有效地通过影响水分子方向来抑制冰核形成. 这项研究阐明了电荷密度在生物适应寒冷环境中的作用.
科学领域:
- 生物化学 生物化学
- 材料科学 材料科学 材料科学
- 物理化学 物理化学
背景情况:
- 生物利用抗蛋白和多糖来适应寒冷.
- 多糖类控制冰形成的确切机制尚不清楚.
研究的目的:
- 研究充电多糖对冰核形成的调节作用.
- 了解多糖与冰相互作用的基本机制.
主要方法:
- 对线性电荷多糖的系统研究.
- 异质冰核化 (HIN) 的实验分析.
- 总频生成 (SFG) 光谱仪用于水分子分析.
主要成果:
- 具有较高负面电荷密度的多糖类更有效地抑制了HIN.
- 冰核化动力学显示出对能量屏障缩放因子 (Γ) 的关键依赖.
- 负电荷的多糖类诱导了水分子界面的显著方向排序.
结论:
- 电荷密度是多糖介导的冰核形成抑制的一个关键因素.
- 多糖类通过改变水界结构来影响冰核形成.
- 这项研究增强了对自然寒冷适应策略的理解.
相关概念视频
Colloidal precipitates
4.8K
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
4.8K
Biosynthesis of Polysaccharides
536
Polysaccharides such as glycogen and starch are synthesized from nucleoside diphosphate sugars, primarily uridine diphosphate glucose (UDPG) and adenosine diphosphate glucose (ADPG). These activated glucose donors act as key intermediates in carbohydrate metabolism and biosynthesis. UDPG primarily involves glycogen synthesis in animals and many bacteria, while ADPG plays a fundamental role in starch synthesis in plants and certain bacteria.UDPG is formed when glucose-1-phosphate reacts with...
536
Proteoglycans
4.6K
Glycans, a class of complex heterogeneous molecules, can be covalently attached to proteins to form glycosylated proteins that regulate various physiological and pathological processes. Glycosylated proteins or glycoproteins comprise N-linked and O-linked oligosaccharides. O-glycosylation is the most common type of protein glycosylation. Here, glycans attach to the oxygen atom of the hydroxyl groups of Serine or Threonine residues. O-linked glycosylation occurs later in protein processing,...
4.6K
Molecular and Ionic Solids
19.8K
Crystalline solids are divided into four types: molecular, ionic, metallic, and covalent network based on the type of constituent units and their interparticle interactions.
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...
19.8K
Intermolecular Forces
68.9K
Atoms and molecules interact through bonds (or forces): intramolecular and intermolecular. The forces are electrostatic as they arise from interactions (attractive or repulsive) between charged species (permanent, partial, or temporary charges) and exist with varying strengths between ions, polar, nonpolar, and neutral molecules. The different types of intermolecular forces are ion–dipole, dipole–dipole, hydrogen bonds, and dispersion; among these, dipole–dipole, hydrogen...
68.9K
Potential Due to a Polarized Object
711
A neutral atom consists of a positively charged nucleus surrounded by a negatively charged electron cloud. When placed in an external electric field, the external electric force pulls the electrons and nucleus apart, opposite to the intrinsic attraction between the nucleus and the electrons. The opposing forces balance each other with a slight shift between the center of masses of the nucleus and the electron cloud, resulting in a polarized atom. On the other hand, a few molecules, like water,...
711


