2000年至2021年间,在23个低收入和中等收入国家的活产儿中,大于妊娠年龄和巨的患病率:个人参与者数据分析
Fati Kirakoya-Samadoulougou1,2, Joyeuse Ukwishaka2, Calypse Ngwasiri2
1Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
BJOG : an international journal of obstetrics and gynaecology
|November 10, 2025
概括
在低收入和中等收入国家 (LMICs) 中,孕期大龄 (LGA) 和宏观病的患病率低于高收入国家. 拉丁美洲和加勒比地区显示,大婴儿的患病率最高.
科学领域:
- 新生儿健康 新生儿健康
- 全球公共卫生 全球公共卫生
- 围产期流行病学 围产期流行病学
背景情况:
- 大于孕期年龄 (LGA) 和宏观症与新生儿和母亲的不良结果有关.
- 流行率在全球不同地区和收入水平之间有很大差异.
- 了解这些变异对于有针对性的公共卫生干预至关重要.
研究的目的:
- 确定2000年至2021年期间23个低收入和中等收入国家 (LMICs) 的LGA和宏观病的患病率.
- 分析这些疾病患病率的区域和时间趋势.
- 将调查结果与高收入国家报告的结果进行比较.
主要方法:
- 进行了一项描述性的多国二次数据分析.
- 分析了来自"脆弱新生儿测量合作"的个人级别数据.
- 从基于人口的队列研究中使用INTERGROWTH-21st标准来定义活产婴儿的LGA和宏观体.
主要成果:
- 在476,939例和313,064例活产中,LGA的中位患病率分别为5.1% (IQR:2.9%-9.6%) 和1.3% (IQR:0.2%-2.4%) 在476,939例和313,064例活产中.
- 在拉丁美洲和加勒比地区,LGA (9.6%) 和宏观体 (3.1%) 的流行率最高.
- 从2000-2010年 (4.9%) 到2011-2021年 (5.9%) 的LGA患病率呈上升趋势,而宏观症患病率保持稳定.
结论:
- 在研究的低收入国家和地区,整体LGA和宏观症的患病率低于高收入国家报告的.
- 在拉丁美洲和加勒比地区,大婴儿的患病率最高.
- 调查结果突出了区域差异,以及在LMICs中需要具体的背景策略.
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