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Updated: Jan 11, 2026

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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LMO4通过诱导RAB17降解和铁灭性耐药性来促进OSCC的进展

JiaJia Fan1, Hongyan Zhang2, Lin Liu3

  • 1Department of Oral Maxillofacial-Head and Neck Surgery, School of Stomatology, China Medical University, Oral Diseases Laboratory of Liaoning, 117 Nanjing North Road, Heping District, Shenyang, Liaoning, 110000, China.

Cell death & disease
|November 10, 2025
PubMed
概括

仅LIM蛋白4 (LMO4) 在口腔状细胞癌 (OSCC) 中升高,通过降低瘤抑制剂RAB17来驱动癌症进展和铁亡抵抗. 针对这种LMO4-RAB17通路可能为OSCC提供新的治疗策略.

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