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Updated: Jan 11, 2026

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诱导细胞自主增殖和肝细胞的代谢重编程

Marina Serra1, Alfredo Smiriglia2, Cristina Migliore3,4

  • 1Department of Biomedical Sciences, University of Cagliari, Monserrato, Italy.

Cell death & disease
|November 10, 2025
PubMed
概括

酸 (LN) 直接导致类似癌症的代谢变化和肝细胞的增殖. 这种重新编程是由核因子红色素衍生的2样2 (NRF2) 途径驱动的,突出显示了它在细胞代谢中的作用.

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After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
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