麦蛋白纳米纤维-铁混合物为铁强化提供了一个稳定,高吸收的铁输送平台
Jiangtao Zhou1,2, Sueppong Gowachirapant3, Christophe Zeder4
1Laboratory of Food and Soft Materials, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
Nature food
|November 10, 2025
概括
新的麦基铁纳米粒子 (OatNF) 为铁强化提供了基于植物的解决方案. 与传统补充剂相比,这些纳米纤维显著增强了铁的吸收,改善了治疗缺铁性贫血的生物可用性.
科学领域:
- 营养科学 营养科学
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
背景情况:
- 全球有20亿人患有缺铁性贫血.
- 目前的铁强化剂在吸收和感官特性方面存在局限性.
- 开发新的,高度生物可利用的铁输送系统至关重要.
研究的目的:
- 引入麦蛋白纳米纤维 (OatNF) 作为超微铁纳米粒子的新型载体.
- 为了设计OatNF以携带铁在铁和铁的形式.
- 评估OatNF杂交物体的铁吸收和感觉特性.
主要方法:
- 麦蛋白纳米纤维 (OatNF) 封装铁纳米粒子的开发.
- 使用不同的还原剂 (亚酸,氧化) 工程铁 (有色/铁) 价值.
- 在缺铁妇女 (n=52) 中进行前性交叉稳定同位素吸收试验.
主要成果:
- 与亚酸盐 (有色铁) 混合的OatNF在水中比硫酸铁的吸收率高1.76倍.
- 与甲酸盐一起使用的OatNF的吸收率是富含多的食物中硫酸铁的1.65倍.
- 与氧化 (铁) 结合的OatNF在反应性食物中表现出良好的吸收和感官特性.
结论:
- OatNF杂交物提供了一种基于植物的策略,用于提供高度生物可利用的铁.
- 与传统强化剂相比,这种新的方法显著提高了铁的吸收.
- OatNF为食品强化提供了一个有前途的解决方案,以对抗缺铁性贫血.
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