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Updated: Jan 11, 2026

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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开发,验证和应用一个中国儿科生理学基础的药动力学模型:强调CYP代谢和脏清除

Rosalind L Southall1, Jean Dinh2, Xian Pan2

  • 1Certara Predictive Technologies, Certara UK Limited, Sheffield, UK. roz.southall@certara.com.

The AAPS journal
|November 10, 2025
PubMed
概括

这项研究开发了一种中国儿科生理学基础的药理动力学 (PBPK) 模型,用于预测儿童的药物行为. 该模型准确地预测了各种药物的药理动力学参数,支持其在不同种族的儿科药物开发中使用.

关键词:
华人中文 华人中文是什么意思在PBPK建模中使用PBPK模型.人类的本体生长过程 (ontogeny)儿科 儿科 儿科 儿科

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