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Updated: Jan 11, 2026

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新型双性DNHD1变异与男性不孕症相关,具有严重的MMAF表型

Islam Uddin1,2, Iqra Zafar1,2, Cao-Ling Xu1,2

  • 1Center for Reproduction and Genetics, Department of Obstetrics and Gynecology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China.

Asian journal of andrology
|November 11, 2025
PubMed
概括

精子鞭子 (MMAF) 的多重形态异常导致男性不孕. 这项研究在巴基斯坦一家家庭中发现了一种新型DNHD1基因变异,负责MMAF,揭示了精子结构缺陷,并扩大了对不孕症原因的理解.

关键词:
亚斯诺特拉托佐索精子缺血症 (asthenoteratozoospermia) 是一个很大的问题.双基突变是一种双基突变.血缘关系是一种血缘关系.男人的不孕不育症.整体外因子测序的测序

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