在患有亚临床甲状腺功能过高症的患者进行血管造影后,对有氧对比剂暴露对甲状腺功能的影响:一项回顾性研究
Zeynep Ece Demirbaş1, Fatma Can2
1Department of Internal Medicine, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Tıbbiye Cad. No:13 Selimiye, Uskudar, Istanbul, 344668, Turkey. zeynepece@gmail.com.
Thyroid research
|November 11, 2025
概括
在亚临床甲状腺功能障碍症患者中,含的对比介质 (ICM) 暴露往往导致甲状腺功能稳定或甲状腺状态平稳. 然而,一些患者可能会发展出临床甲状腺功能过强或甲状腺功能低下症,需要仔细监测.
科学领域:
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
- 心脏病学 心脏病学
背景情况:
- 亚临床甲状腺功能障碍症在需要增强对比度的手术的患者的管理中提出了挑战.
- 对这种人群来说,研究含的对比介质 (ICM) 对甲状腺功能的影响至关重要.
研究的目的:
- 评估ICM暴露对先前存在的亚临床甲状腺功能过高的患者甲状腺功能的影响.
- 评估甲状腺刺激激素 (TSH),自由三甲状腺素 (fT3) 和自由甲状腺素 (fT4) 水平在ICM给药后的变化.
主要方法:
- 对46名患有亚临床甲状腺功能障碍症的患者进行了回顾性分析,这些患者接受了血管造影手术.
- 在ICM暴露之前和之后的甲状腺功能测试 (TSH,ft3,ft4) 的比较.
- 分层成低 (<200毫升) 和高 (≥200毫升) 的ICM体积组.
主要成果:
- 50%的患者甲状腺功能正常化 (euthyroid),而41.3%的患者在ICM后仍然存在亚临床甲状腺功能过高.
- 一小部分人患有明显的甲状腺功能过高 (4.3%) 或甲状腺功能低下 (4.3%).
- 在手术后观察到TSH水平显著增加 (p<0.01),FT3或FT4没有显著变化.
结论:
- 在亚临床甲状腺功能过高患者中,ICM暴露通常导致甲状腺功能稳定或正常化.
- 临床甲状腺功能障碍或甲状腺功能障碍可能发生,强调需要警监测.
- 建议进行进一步的长期跟踪,以充分了解该队列中ICM相关的风险.
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