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Updated: Jan 11, 2026

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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分泌的线粒体阿斯巴丁-tRNA合成酶 (DARS2) 调节TNFα信号传递

Benjamin S Johnson1, Alex Cornwell1, Daniela Farkas1

  • 1Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, The Ohio State University, Columbus, Ohio, USA.

Physiological reports
|November 11, 2025
PubMed
概括

线粒体阿斯巴丁-tRNA合成酶 (DARS2) 在TNFα刺激后从呼吸道细胞分泌出来. 这种释放的DARS2在巨细胞中诱导一种类似M1的表型,突出显示了一种新的膜信号通路.

关键词:
在DARS2中,你会看到DARS2.细胞因子细胞因子肺部上皮质 肺部上皮质线粒体中的线粒体.

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