胸壁切除在老年非小细胞肺癌中是否安全?
Ozkan Saydam1, Celal Bugra Sezen1, Melike Ülker1
1Department of Thoracic Surgery, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey.
The clinical respiratory journal
|November 11, 2025
概括
高龄并不影响经过胸壁切除的非小细胞肺癌 (NSCLC) 患者的结果. 手术方法和疾病阶段是生存和并发症的关键预后因素.
科学领域:
- 胸部外科手术 胸部外科手术
- 手术瘤学手术瘤学
- 老年瘤学 老年瘤学
背景情况:
- 非小细胞肺癌 (NSCLC) 是癌症相关死亡的主要原因.
- 胸壁切除是局部晚期NSCLC的关键手术干预.
- 对老年癌症患者评估与年龄相关的结果对于治疗规划至关重要.
研究的目的:
- 评估NSCLC患者胸壁切除的安全性和有效性.
- 为了比较年轻和年长的成年患者群体之间的手术结果.
- 为了确定影响NSCLC手术并发症和生存的预后因素.
主要方法:
- 对160名经过胸壁切除 (2009-2019) 的NSCLC患者的回顾性分析.
- 患者分为两个年龄组:70岁以下 (A组) 和70岁及以上 (B组).
- 分析的结果包括并发症率,生存率以及与患者人口统计学,并发症和手术程序的相关性.
主要成果:
- 整体并发症率为28.1%,年龄组之间没有显著差异.
- 并发症的风险与切除的肋骨数量相关 (p=0.035).
- A组的生存率为72%,B组的生存率为93% (p=0.189). 脊椎切除术后的生存率 (85%) 与肺切除术 (41%,p<0.001) 相比显著更高.
结论:
- 高龄不是NSCLC胸壁切除后并发症或生存的预后因素.
- 手术切除的类型 (肺切除术与肺切除术) 和疾病阶段是最重要的预后因素.
- 这些发现支持老年NSCLC患者的积极外科治疗,如果根据疾病阶段表明.
相关概念视频
01:26Flail Chest-II
Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
Assessment:
1. Clinical Evaluation:
History:
01:27Pneumothorax-II
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations: